What adverse effect is commonly associated with the use of Mebendazole?

Mebendazole, an anthelmintic agent, is primarily used to treat a variety of helminthic infections. One of the most commonly reported adverse effects associated with its use is abdominal cramps. This occurs due to the drug's action on the intestines where it disrupts the metabolism of the parasites, leading to their death and subsequent passage through the gastrointestinal tract. As the body responds to the presence of dead parasites, it can result in discomfort and cramping.

While other adverse effects such as nausea and vomiting, headaches, dizziness, and skin rash can occur with medications, they are less commonly associated with Mebendazole. Abdominal cramps, however, are directly linked to the drug's mechanism of action and are frequently reported among patients undergoing treatment. Understanding the pharmacological profile of Mebendazole helps in anticipating and managing these adverse effects during treatment.