What is the therapeutic use of Niclosamide?

Niclosamide is an anthelmintic agent specifically designed for the treatment of cestode infections, which are caused by tapeworms. It works by inhibiting the oxidative phosphorylation in the cestode's mitochondria, effectively reducing the ATP production necessary for the tapeworm’s survival and growth. By disrupting the energy metabolism of the parasites, Niclosamide leads to their eventual death.

This selective action makes it a highly effective treatment option for infections caused by species such as Taenia solium (pork tapeworm) and Taenia saginata (beef tapeworm). It's important to note that Niclosamide is not effective against other types of infections, such as those caused by viruses, bacteria, or fungi, which further clarifies its specific therapeutic use in targeting cestodal infections.