Which of the following statements is true regarding mebendazole?

Mebendazole is indeed a widely used broad-spectrum anthelmintic. This means that it is effective against a variety of intestinal helminths, including roundworms, hookworms, and whipworms. Its mechanism of action involves inhibiting the synthesis of microtubules in the parasites, leading to their immobilization and death. This broad-spectrum capability makes it a popular choice in different clinical settings for treating parasitic infections.

Other options present misunderstandings about mebendazole's administration and treatment regimen. It is typically administered orally, and while it can be effective with single doses in some cases, it may require multiple doses over several days to achieve the best therapeutic outcomes, particularly for certain infections. Long-term treatment plans are generally not necessary for mebendazole as it is effective with short-term regimens; however, re-treatment may be required for specific infections or reinfestations. Understanding these aspects helps in effectively using mebendazole in clinical practice.