Which type of meals should be avoided when administering anthelmintic drugs?

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When administering anthelmintic drugs, it is advisable to avoid high-fat meals. Anthelmintic medications work by targeting the metabolic processes of the parasites, and high-fat meals can influence the absorption of these drugs. Fatty meals may impede the effectiveness of certain anthelmintics, such as Albendazole and Mebendazole, by altering gastrointestinal motility and the drug's solubility, potentially leading to suboptimal drug levels in the body.

In contrast, other types of meals, such as those high in fiber, sugar, or protein, do not significantly affect the pharmacokinetics of most anthelmintic agents. High-fiber diets may even enhance digestive health but do not specifically interfere with the absorption or action of anthelmintics. Therefore, the recommendation remains to avoid high-fat meals to ensure that the anthelmintic can be absorbed properly and exert its full effect against the parasites.

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